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From Data to Discovery Uniting Africa Against Amyloidosis

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Category Blog

25 Aug

Organ Transplantation in Amyloidosis: When Is It Considered?

Organ transplantation can be an important treatment option for carefully selected patients with amyloidosis and advanced organ dysfunction. This article explains when heart, kidney, liver, or combined transplantation may be considered in AL, ATTR, and AA amyloidosis, and why disease control and multidisciplinary assessment are essential.

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21 Aug

Biopsy in Cardiac Amyloidosis: Tissue Diagnosis, Congo Red Staining and Amyloid Typing

Biopsy remains important when cardiac amyloidosis cannot be diagnosed confidently by non-invasive testing. Learn when tissue sampling is needed, how Congo red confirms amyloid, and why accurate amyloid typing is essential.

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21 Aug

Genetic Testing in Transthyretin Cardiac Amyloidosis: ATTRv, ATTRwt and Family Screening

Genetic testing helps distinguish hereditary ATTR amyloidosis from wild-type disease. Learn when to test, how TTR variants are interpreted, and what results mean for patients and their families.

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21 Aug

Monoclonal Protein Testing in Cardiac Amyloidosis: Free Light Chains, Immunofixation and AL Screening

Monoclonal protein testing is a critical step in the evaluation of suspected cardiac amyloidosis. Learn how serum free light chains and serum and urine immunofixation help identify possible AL amyloidosis and guide the diagnostic pathway toward an accurate amyloid subtype diagnosis.

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19 Aug

Cardiac Magnetic Resonance Imaging in Cardiac Amyloidosis: LGE, T1 Mapping and ECV

Cardiac magnetic resonance imaging provides detailed tissue characterization in cardiac amyloidosis. Learn how late gadolinium enhancement, native T1 mapping, extracellular volume and abnormal myocardial nulling support diagnosis and assessment.

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19 Aug

Bone Scintigraphy Imaging of Cardiac Amyloidosis: PYP, DPD, HMDP, Perugini Grading and Diagnostic Interpretation

Bone scintigraphy is central to the non-invasive diagnosis of transthyretin cardiac amyloidosis. This article explains PYP, DPD and HMDP imaging, Perugini grading, SPECT, the H/CL ratio, monoclonal protein testing and when biopsy is still required.

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